There is strong clinical evidence of the safety and effectiveness of DUROLANE. There are more clinical studies of DUROLANE than any other single-injection hyaluronic acid knee therapy.
During the DUROLANE pivotal trial:2
- No serious adverse events were considered related to DUROLANE treatment.2
- The most common adverse events were arthralgia (8.6%), injection site pain (2.3%), and joint swelling (1.7%).2
DUROLANE is safe for repeated courses of therapy. Repeat administration of a course of DUROLANE therapy does not increase the incidence of adverse events.2,4